Pharmaceutics, Free Full-Text
Por um escritor misterioso
Descrição
The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914, that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood–brain barrier (BBB). Owing to restricted transport across the BBB, FDA-approved drugs for the CNS have been generally limited to lipid-soluble small molecules. Drugs that do not cross the BBB can be re-engineered for transport on endogenous BBB carrier-mediated transport and receptor-mediated transport systems, which were identified during the 1970s–1980s. By the 1990s, a multitude of brain drug delivery technologies emerged, including trans-cranial delivery, CSF delivery, BBB disruption, lipid carriers, prodrugs, stem cells, exosomes, nanoparticles, gene therapy, and biologics. The advantages and limitations of each of these brain drug delivery technologies are critically reviewed.
Bioavailability and Bioequivalence Research Facility, University
Pharmacy PowerPoint Template
Conical Pharmaceuticals
GPAT 2024 - Graduate Pharmacy by EduGorilla Prep Experts
AAPS PharmSciTech
PDF) A Textbook of Social and Preventive Pharmacy
A TEXT BOOK OF PHARMACEUTICS-I
Unit 2 - Pharmaceutics 1 - 1st Semester - B Pharmacy Notes
CanadaCSPS (@CanadaCSPS) / X
de
por adulto (o preço varia de acordo com o tamanho do grupo)